The principal cytochrome P450 isoenzyme concerned seems for being CYP2E1, with CYP1A2 and CYP3A4 as supplemental pathways. Around eighty five% of an oral dose appears in the urine inside 24 hours of administration, most because the glucuronide conjugate, with tiny amounts of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity facts.Th… Read More